According to expert, contrast-induced nephropathy (CIN) is the third leading cause of hospital-acquired acute renal injury accounting for about 12 per cent of cases across the world. CIN remains a significant concern in cardiology, but awareness, risk assessment, and preventive measures can mitigate its impact.
In India, the numbers reflect the worldwide prevalence and are more common in the northern part of India with an estimate of 15 per cent (Image: Freepik)
New Delhi: Contrast-induced nephropathy (CIN) is the third leading cause of hospital-acquired acute renal injury accounting for about 12 per cent of cases across the world. The condition is associated with a higher risk of in-hospital and 1-year mortality even in patients who do not require dialysis. Moreover, there is a complicated relationship between CIN, comorbidity and mortality. Most patients who develop CIN do not die from kidney failure.
Dr Gopi A, Director – Interventional Cardiology, Fortis Hospital, Cunningham Road, Bangalore told News9, “CIN remains a significant concern in cardiology, but awareness, risk assessment, and preventive measures can mitigate its impact. Ongoing research holds promise for further reducing the risk and improving outcomes for patients undergoing cardiac procedures with contrast media.”
Risk Factors:
Various factors increase the risk of CIN, including:
• Pre-existing kidney condition: This is one of the most critical risk factors to watch out for.
• Diabetes: Diabetics are more susceptible to kidney damage.
• Age: Older people are at a higher risk.
• Volume and type of contrast: Larger volumes and certain types of contrast media pose a higher risk.
• Heart failure and other medical conditions: These can further strain the kidneys.
Prevention and Management:
While there’s no foolproof way to prevent CIN, strategies can minimise the risk:
• Identifying high-risk patients: Careful assessment of risk factors allows for tailored preventive measures.
• Hydration: Maintaining proper hydration before, during, and after contrast administration is important
• Alternative imaging techniques: In some cases, alternative imaging techniques without contrast may be considered.
• Medications: Certain drugs or treatments can help kidney decline.
Current Research and Future Outlook:
Researchers are actively exploring new strategies for CIN prevention and management, including:
• Novel contrast media with reduced nephrotoxicity.
• Biomarkers for early detection and risk stratification.
• Protective medications with improved efficacy and safety profiles.
Follow us on social media
